SCHEMBL5489495

SCHEMBL5489495

COCC(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.62
TSHR P16473 1/20 0.58
ACE P12821 5/20 0.57
GPR34 Q9UPC5 1/20 0.56
FPR2 P25090 2/20 0.56
MME P08473 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2247123 1.00 PSMB5 (0.62) PSMB5TSHRACEGPR34FPR2
SCHEMBL21583769 0.89 ALDH1A1 (0.65) PSMB5L3MBTL1
SCHEMBL21583766 0.89 ALDH1A1 (0.65) PSMB5L3MBTL1
SCHEMBL20798175 0.87 L3MBTL1 (0.52) PSMB5ACEGPR34FPR2MME
SCHEMBL20798174 0.87 L3MBTL1 (0.52) PSMB5ACEGPR34FPR2MME
SCHEMBL11036712 0.86 L3MBTL1 (0.51) PSMB5ACEGPR34FPR2MME
SCHEMBL23201777 0.85 PSMB5 (0.63) PSMB5ACEFPR2L3MBTL1
SCHEMBL21583746 0.85 PSMB5 (0.63) PSMB5ACEFPR2L3MBTL1
SCHEMBL9417473 0.83 GPR34 (0.62) ACEGPR34MMENPSR1
SCHEMBL7296506 0.83 GPR34 (0.73) PSMB5GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805237-B1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND JIANGSU CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) 2026-01-28 EP disclosed
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2023-01-03 US disclosed
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2021-07-15 US disclosed
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed
US-9492467-B2 Rapid-acting insulin formulation comprising an oligosaccharide ADOCIA (FR) 2016-11-15 US disclosed
US-20150231160-A1 RAPID-ACTING INSULIN FORMULATION COMPRISING AN OLIGOSACCHARIDE ADOCIA (FR) 2015-08-20 US disclosed
US-9018190-B2 Functionalized oligosaccharides ADOCIA (FR) 2015-04-28 US disclosed
US-20130231281-A1 Rapid acting insulin formulation comprising an oligosaccharide ADOCIA (FR) 2013-09-05 US disclosed
WO-2013064787-A1 QUICK-ACTING INSULIN FORMULATION INCLUDING AN OLIGOSACCHARIDE ADOCIA (FR) 2013-05-10 WO disclosed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 EP disclosed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF SEM1, VIP, PSMB11 PSMB5 38/4885TSHR 2413/4885ACE 137/4885
US-20130231281-A1 Rapid acting insulin formulation comprising an oligosaccharide IAPP, INSR, IDE PSMB5 463/4885TSHR 874/4885ACE 1189/4885
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof SEM1, VIP, PSMB11 PSMB5 38/4885TSHR 2413/4885ACE 137/4885
US-20150231160-A1 RAPID-ACTING INSULIN FORMULATION COMPRISING AN OLIGOSACCHARIDE IAPP, IDE, INSR PSMB5 739/4885TSHR 918/4885ACE 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.