Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026728 | 0.78 | MEN1 (0.64) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL4515174 | 0.77 | KMT2A (0.58) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL8411315 | 0.73 | MEN1 (0.56) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL11036674 | 0.72 | MEN1 (0.55) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL610584 | 0.70 | NPC1 (1.00) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL11036692 | 0.69 | DRD2 (0.56) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL10887685 | 0.68 | MEN1 (0.58) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL30165841 | 0.68 | MEN1 (0.49) | MEN1NPC1RAB9AKMT2ADRD2 | |
| SCHEMBL14600367 | 0.67 | NR1H4 (0.48) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2234870 | 0.66 | MEN1 (0.72) | MEN1NPC1RAB9AKMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528297-A | Neuroleptic 3-azetidinylethyl-1-phenyl-2-imidazolidinones | GRUPPO LEPETIT S.P.A. (IT) | 1985-07-09 | — | — | US | disclosed |
| US-4528297-A | Neuroleptic 3-azetidinylethyl-1-phenyl-2-imidazolidinones | GRUPPO LEPETIT S.P.A. (IT) | 1985-07-09 | — | — | US | disclosed |
| US-4528297-A | Neuroleptic 3-azetidinylethyl-1-phenyl-2-imidazolidinones | GRUPPO LEPETIT S.P.A. (IT) | 1985-07-09 | — | — | US | disclosed |