Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016599 | 0.88 | SRD5A2 (0.50) | ABCB11PTGS2SRD5A2KMT2AALDH1A1 | |
| SCHEMBL13983012 | 0.85 | THRB (0.44) | ABCB11PTGS2SRD5A2THRBNPSR1 | |
| SCHEMBL10920459 | 0.85 | KMT2A (0.44) | NPSR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11015971 | 0.84 | SRD5A2 (0.50) | ABCB11PTGS2SRD5A2THRBKMT2A | |
| SCHEMBL11018074 | 0.82 | ALDH1A1 (0.49) | NPSR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL7675435 | 0.82 | PTGS2 (0.57) | ABCB11PTGS2SRD5A2THRBNPSR1 | |
| SCHEMBL11017123 | 0.80 | MEN1 (0.50) | SRD5A2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8399669 | 0.80 | ABCB11 (0.48) | ABCB11PTGS2SRD5A2THRBALDH1A1 | |
| SCHEMBL11017238 | 0.80 | ABCB11 (0.43) | ABCB11PTGS2SRD5A2THRBKMT2A | |
| SCHEMBL11016429 | 0.78 | CNR2 (0.54) | THRBNPSR1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152542-A1 | Pyrrol-3-carboxylic acids having central analgesic activity | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1985-08-28 | — | — | EP | claimed |