Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 7/20 | 0.48 |
| ▸ | REN | P00797 | 8/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014003 | 0.80 | REN (0.47) | CTSDRENCDK4CCNA2CCND1 | |
| SCHEMBL9417355 | 0.78 | REN (0.47) | REN | |
| SCHEMBL30599003 | 0.78 | CCNA2 (0.51) | CDK4CCNA2CCND1CDK2CCNA1 | |
| SCHEMBL15272522 | 0.77 | OPRM1 (0.50) | CTSDRENCTSBCTSK | |
| SCHEMBL15272531 | 0.77 | OPRM1 (0.50) | CTSDRENCTSBCTSK | |
| SCHEMBL11011996 | 0.77 | REN (0.57) | RENCTSBCTSK | |
| SCHEMBL9716847 | 0.77 | REN (0.66) | CTSDRENCTSBCTSK | |
| SCHEMBL11012331 | 0.76 | REN (0.51) | RENCTSBCTSK | |
| SCHEMBL9716892 | 0.76 | REN (0.65) | REN | |
| SCHEMBL9417466 | 0.76 | REN (0.56) | RENCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |