Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303857 | 0.84 | POLB (0.43) | ALDH1A1LMNAPOLBNAAAZDHHC20 | |
| SCHEMBL19215358 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBNAAAZDHHC20 | |
| SCHEMBL1104022 | 0.74 | NAAA (0.43) | ALDH1A1LMNANAAAZDHHC20ZDHHC2 | |
| SCHEMBL1104020 | 0.71 | POLB (0.40) | ALDH1A1LMNAPOLBNAAAABCC4 | |
| SCHEMBL3590647 | 0.71 | POLB (0.40) | ALDH1A1LMNAPOLBNAAAABCC4 | |
| SCHEMBL14850987 | 0.68 | POLB (0.35) | ALDH1A1LMNAPOLBABCC4MAPT | |
| SCHEMBL17121284 | 0.68 | POLB (0.41) | ALDH1A1LMNAPOLBABCC4MAPT | |
| SCHEMBL12951832 | 0.68 | DDAH1 (0.33) | ALDH1A1LMNAPOLBNAAAABCC4 | |
| SCHEMBL24072308 | 0.67 | NAAA (0.51) | POLBNAAAPRCPGNAI3GNAO1 | |
| SCHEMBL1101671 | 0.67 | ALOX15 (0.31) | ALDH1A1LMNAABCC4MAPTDDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153800-B2 | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2012-04-10 | — | — | US | disclosed |