Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24982808 | 0.78 | NAAA (0.50) | NAAAKMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL30945968 | 0.77 | GNAI3 (0.64) | NAAAKMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL10303857 | 0.76 | POLB (0.43) | NAAAKMT2AALDH1A1LMNAABCC4 | |
| SCHEMBL19215358 | 0.75 | ALDH1A1 (0.42) | NAAAKMT2AALDH1A1LMNAPRCP | |
| SCHEMBL1103811 | 0.74 | ALDH1A1 (0.35) | NAAAGNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL13618531 | 0.70 | ADRA1A (0.51) | NAAAGNAI3GNAO1GNAI1 | |
| SCHEMBL24982662 | 0.70 | NAAA (0.51) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL18239793 | 0.70 | NAAA (0.47) | NAAAGNAI3GNAO1GNAI1PRCP | |
| SCHEMBL20859582 | 0.70 | MEN1 (0.65) | KMT2AALDH1A1LMNATSHRABCC4 | |
| SCHEMBL13058102 | 0.70 | MEN1 (0.65) | KMT2AALDH1A1LMNATSHRABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153800-B2 | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2012-04-10 | — | — | US | disclosed |