Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11038891 | 0.98 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL11038182 | 0.76 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL11040454 | 0.76 | FYN (0.32) | — | |
| Hydrochloric Acid SCHEMBL11060175 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL11041640 | 0.72 | BRD4 (0.45) | — | |
| SCHEMBL11055073 | 0.71 | POLB (0.32) | — | |
| Hydrochloric Acid SCHEMBL11060184 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL11040043 | 0.71 | BRD4 (0.44) | — | |
| Hydrochloric Acid SCHEMBL11038881 | 0.68 | BRD4 (0.38) | — | |
| SCHEMBL9134207 | 0.68 | TRPA1 (0.37) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | claimed |