SCHEMBL11055073

SCHEMBL11055073

CCOC1=NC=Cc2cc3c(cc2C1)CCC3

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11042221 0.82 ALDH1A1 (0.33)
SCHEMBL11039717 0.79 BRD4 (0.41)
SCHEMBL11039613 0.71 NOS3 (0.32)
Hydrochloric Acid SCHEMBL11038891 0.70 NOS3 (0.32)
Hydrochloric Acid SCHEMBL11043286 0.67 NOS3 (0.35)
Hydrochloric Acid SCHEMBL11040765 0.65 TSHR (0.36) POLB
SCHEMBL11041298 0.64 BRD4 (0.46)
SCHEMBL11057303 0.62 MAPT (0.40)
SCHEMBL11040367 0.62 MAPT (0.40)
Hydrochloric Acid SCHEMBL11051850 0.61 MAPT (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0116444-A2 Improvements in or relating to benzazepine derivatives ELI LILLY AND COMPANY (US) 1984-08-22 EP claimed