Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043419 | 0.86 | ALDH1A1 (0.45) | PTGS2PTGS1MAPTNPSR1ALDH1A1 | |
| SCHEMBL11040285 | 0.84 | ALDH1A1 (0.48) | PTGS2MAPTALDH1A1PPARDKDM4E | |
| SCHEMBL11037282 | 0.76 | ALOX5 (0.41) | PTGS2MAPTALDH1A1PPARDALOX5 | |
| SCHEMBL11040057 | 0.74 | PTGS2 (0.48) | PTGS2PTGS1MAPTNPSR1L3MBTL1 | |
| SCHEMBL11043713 | 0.73 | ADORA2A (0.36) | MAPTL3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL11563598 | 0.71 | PTGS2 (0.56) | PTGS2PTGS1MAPTNPSR1L3MBTL1 | |
| SCHEMBL11284673 | 0.71 | PTGS2 (0.45) | PTGS2PTGS1MAPTNPSR1ACHE | |
| SCHEMBL11747669 | 0.70 | PPARA (0.56) | PTGS2PTGS1PPARDPTGDR2KDM4E | |
| SCHEMBL11041686 | 0.70 | HRH3 (0.43) | PTGS2PTGS1ACHEPPARDALOX5 | |
| SCHEMBL11288708 | 0.70 | HTT (0.44) | PTGS2PTGS1MAPTNPSR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |