Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043419 | 0.86 | ALDH1A1 (0.45) | LMNAMAPTKDM4EHRH3PKM | |
| SCHEMBL11037282 | 0.81 | ALOX5 (0.41) | ADORA2AADORA1TGFBR1NPC1MAPT | |
| SCHEMBL11039850 | 0.73 | PTGS2 (0.41) | L3MBTL1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11040285 | 0.71 | ALDH1A1 (0.48) | LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL11463722 | 0.66 | IDO1 (0.57) | ADORA2AADORA1IDO1NPC1MAPT | |
| SCHEMBL9368570 | 0.65 | MAPK14 (0.47) | ADORA2AADORA1TGFBR1NPC1MAPT | |
| SCHEMBL11471961 | 0.64 | EHMT2 (0.48) | L3MBTL1LMNANPC1MAPTRAB9A | |
| SCHEMBL8240373 | 0.64 | TGFBR1 (0.55) | ADORA2AADORA1TGFBR1MAPTALDH1A1 | |
| Bromide SCHEMBL9376098 | 0.64 | MAPK14 (0.46) | ADORA2AADORA1TGFBR1NPC1MAPT | |
| SCHEMBL18230394 | 0.63 | TGFBR1 (0.58) | TGFBR1LMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |