Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771609 | 0.89 | ALOX5 (0.61) | SMN1; SMN2TSHRALOX5GAAALDH1A1 | |
| SCHEMBL11047148 | 0.81 | MAOA (0.63) | MAOAMAOBSMN1; SMN2TP53EPHX1 | |
| SCHEMBL13648229 | 0.78 | SMN1; SMN2 (0.70) | MAOAMAOBSMN1; SMN2TP53EPHX1 | |
| SCHEMBL2688879 | 0.78 | EPHX2 (0.61) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11059378 | 0.78 | SMN1; SMN2 (0.94) | MAOAMAOBSMN1; SMN2TP53EPHX1 | |
| SCHEMBL10906841 | 0.77 | TSHR (0.78) | MAOAMAOBSMN1; SMN2TP53EPHX1 | |
| SCHEMBL6833118 | 0.76 | EPHX2 (0.59) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL10906039 | 0.76 | PTGS2 (0.79) | MAOAMAOBSMN1; SMN2TP53EPHX1 | |
| SCHEMBL13042440 | 0.76 | ALOX5 (0.68) | SMN1; SMN2TSHRALOX5GAAALDH1A1 | |
| Diphenylurea SCHEMBL133103 | 0.75 | SMN1; SMN2 (1.00) | MAOAMAOBSMN1; SMN2TP53EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481285-A | IMPROVED SHAPPNESS AND EDGE EFFECTS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-06 | — | — | US | disclosed |