SCHEMBL11040253

SCHEMBL11040253

C=Cc1ccc(B(O)O)cc1B(O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.47
ENPP2 Q13822 5/20 0.42
CA2 P00918 4/20 0.38
LPL P06858 2/20 0.38
LIPG Q9Y5X9 2/20 0.38
CA1 P00915 3/20 0.38
KDM4E B2RXH2 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7996644 0.78 ERN1 (0.38) CA2CA1KDM4ETSHR
SCHEMBL34463734 0.78 TTR (0.46) TTRENPP2CA2CA1KDM4E
SCHEMBL22117220 0.78 NFE2L2 (0.34) KDM4E
SCHEMBL26067953 0.77 TTR (0.46) TTRENPP2CA2LPLLIPG
SCHEMBL31365992 0.73 TTR (0.41) TTRENPP2CA2CA1KDM4E
SCHEMBL28440353 0.73 MGLL (0.42) CA2CA1KDM4E
SCHEMBL22291991 0.73 TTR (0.46) TTRENPP2CA2CA1KDM4E
SCHEMBL13636336 0.73 ENPP2 (0.42) TTRENPP2CA2CA1KDM4E
SCHEMBL29418119 0.71 ALDH1A1 (0.44) ENPP2LIPGTSHR
SCHEMBL393924 0.71 ALDH1A1 (0.44) ENPP2LIPGTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59227907-A None JP disclosed
JP-S59227907-A PRODUCTION OF BORIC ACID GROUP-CONTAINING POLYMER PARTICLE JAPAN SYNTHETIC RUBBER CO LTD 1984-12-21 JP disclosed