Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 9/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CTSH | P09668 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668348 | 0.82 | ACE (0.48) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL10668345 | 0.82 | ACE (0.48) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL11037577 | 0.81 | ITGB3 (0.41) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL11037582 | 0.81 | ITGB3 (0.41) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL10663870 | 0.78 | ITGB3 (0.41) | CTSKCTSS | |
| SCHEMBL9716618 | 0.73 | CPB2 (0.55) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL7890166 | 0.73 | CPB2 (0.55) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL19982999 | 0.73 | CTSB (0.56) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL19983285 | 0.73 | CTSB (0.56) | CTSBCTSKCTSSCTSHCTSL | |
| SCHEMBL19983212 | 0.73 | CTSB (0.56) | CTSBCTSKCTSSCTSHCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |