Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037582 | 1.00 | ITGB3 (0.41) | ITGB3ITGA2BACECTSVCTSL | |
| SCHEMBL11040565 | 0.81 | CTSB (0.47) | ACECTSVCTSLCTSBCTSH | |
| SCHEMBL10668345 | 0.70 | ACE (0.48) | ACECTSVCTSLCTSBCTSH | |
| SCHEMBL10668348 | 0.70 | ACE (0.48) | ACECTSVCTSLCTSBCTSH | |
| SCHEMBL11404366 | 0.69 | ITGB3 (0.52) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL11404359 | 0.69 | ITGB3 (0.52) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL10666091 | 0.69 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7890166 | 0.65 | CPB2 (0.55) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL9716618 | 0.65 | CPB2 (0.55) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL10663870 | 0.63 | ITGB3 (0.41) | ITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |