Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 9/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSH | P09668 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668348 | 1.00 | ACE (0.48) | ACECTSBCTSKCTSSCTSH | |
| SCHEMBL11075153 | 0.89 | ACE (0.38) | ACE | |
| SCHEMBL11040565 | 0.82 | CTSB (0.47) | ACECTSBCTSKCTSSCTSH | |
| SCHEMBL10667341 | 0.73 | TDP1 (0.43) | ACE | |
| SCHEMBL11036872 | 0.72 | CTSK (0.43) | ACECTSKCTSS | |
| SCHEMBL10663870 | 0.72 | ITGB3 (0.41) | CTSKCTSS | |
| SCHEMBL11398388 | 0.71 | REN (0.46) | ACECTSKCTSS | |
| SCHEMBL11398373 | 0.71 | REN (0.46) | ACECTSKCTSS | |
| SCHEMBL11407330 | 0.70 | — | — | |
| SCHEMBL9829694 | 0.70 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | disclosed |