Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158078 | 0.76 | — | — | |
| SCHEMBL11040536 | 0.74 | NOS1 (0.49) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL11040319 | 0.72 | KMO (0.34) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL9954750 | 0.70 | GRM5 (0.37) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL11282616 | 0.70 | MCL1 (0.33) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL9385343 | 0.67 | NOS1 (0.38) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL14280505 | 0.65 | NOS1 (0.39) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL520456 | 0.64 | NOS1 (0.41) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL9380376 | 0.64 | NOS1 (0.41) | NOS1NOS3NOS2MCL1KMO | |
| SCHEMBL14126363 | 0.63 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045892-B1 | PROCESS FOR THE PREPARATION OF PRECURSORS FOR POLYMERS CONTAINING THE OXAZOLIN-2-ONE RING, AND THEIR USE IN THE PRODUCTION OF HIGH MOLECULAR WEIGHT POLYMERS | BAYER AG (DE) | 1984-02-01 | — | — | EP | disclosed |
| EP-0050780-B1 | ISOCYANATO-OXAZOLINONES, METHOD FOR THE PREPARATION OF OXAZOLIDIN-2-ONE RINGS CONTAINING PLASTICS PRECURSORS, AND THEIR USE IN THE PREPARATION OF HIGH-MOLECULAR PLASTICS | BAYER AG (DE) | 1983-12-28 | — | — | EP | disclosed |
| US-4350781-A | Process for the preparation of polymer precursors containing oxazolin-2-one rings | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0050780-A1 | Isocyanato-oxazolinones, method for the preparation of oxazolidin-2-one rings containing plastics precursors, and their use in the preparation of high-molecular plastics | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0045892-A1 | Process for the preparation of precursors for polymers containing the oxazolin-2-one ring, and their use in the production of high molecular weight polymers | BAYER AG (DE) | 1982-02-17 | — | — | EP | disclosed |