SCHEMBL1104128

SCHEMBL1104128

C=C(C)COOc1ccc(NC(=O)C(C)(C)CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.45
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 3/20 0.39
CYP1A2 P05177 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
S1PR4 O95977 2/20 0.38
S1PR1 P21453 2/20 0.38
S1PR3 Q99500 2/20 0.38
S1PR5 Q9H228 2/20 0.38
HTT P42858 2/20 0.38
PDK1 Q15118 1/20 0.38
PDK2 Q15119 1/20 0.38
PDK3 Q15120 1/20 0.38
PDK4 Q16654 1/20 0.38
BRD4 O60885 1/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104156 0.85 KMT2A (0.47) KMT2AMEN1TDP1LMNACYP1A2
SCHEMBL12863518 0.84 KMT2A (0.43) KMT2AMEN1TDP1LMNACYP1A2
SCHEMBL9883772 0.78 ELANE (0.44) GPR174KMT2AMEN1TDP1SMN1; SMN2
SCHEMBL1104139 0.78 RAB9A (0.46) KMT2AMEN1TDP1SMN1; SMN2HSD17B10
SCHEMBL12226380 0.78 L3MBTL1 (0.61) KMT2AMEN1TDP1LMNAL3MBTL1
SCHEMBL14582701 0.77 GAA (0.51) KMT2AMEN1TDP1SMN1; SMN2HSD17B10
SCHEMBL1104169 0.77 PDK1 (0.60) KMT2AMEN1TDP1SMN1; SMN2LMNA
SCHEMBL13932958 0.76 KMT2A (0.46) GPR174KMT2AMEN1TDP1LMNA
SCHEMBL13756068 0.76 KMT2A (0.44) GPR174KMT2AMEN1TDP1LMNA
SCHEMBL13921995 0.76 CA1 (0.49) GPR174KMT2AMEN1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-7771916-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-08-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed