Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782200 | 0.75 | — | — | |
| SCHEMBL11048262 | 0.75 | LMNA (0.33) | ALDH1A1LMNA | |
| SCHEMBL6461960 | 0.69 | CYP4F2 (0.58) | ALDH1A1CYP4F2CYP4A11LMNAHSD17B10 | |
| SCHEMBL9715269 | 0.69 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL7971410 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL2170282 | 0.68 | — | — | |
| SCHEMBL6560711 | 0.67 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL5611272 | 0.67 | MEN1 (0.57) | SMN1; SMN2ALDH1A1CYP4F2CYP4A11LMNA | |
| SCHEMBL7973321 | 0.67 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL6268325 | 0.67 | CYP4F2 (0.65) | SMN1; SMN2ALDH1A1CYP4F2CYP4A11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440947-A | Preparation of substituted alpha-halogeno-propionic acids and their derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-04-03 | — | — | US | disclosed |
| EP-0061629-A2 | Process for the preparation of substituted alpha-halopropionic acids and of their derivatives; substituted vinylidene chloride | BAYER AG (DE) | 1982-10-06 | — | — | EP | disclosed |