SCHEMBL6461960

SCHEMBL6461960

CCOC(=O)C(C)(C)CCCl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.58
CYP4A11 Q02928 3/20 0.58
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PKM P14618 3/20 0.40
THRB P10828 1/20 0.40
ABCB11 O95342 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
HTR2A P28223 1/20 0.40
PMP22 Q01453 1/20 0.40
PPARA Q07869 1/20 0.40
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MMP8 P22894 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6268325 0.88 CYP4F2 (0.65) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL2021436 0.86 CYP4F2 (0.67) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL28404067 0.86 CYP4F2 (0.68) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL2993978 0.84 CYP4F2 (0.71) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL22819335 0.84 CYP4F2 (0.71) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL5306680 0.82 CYP4F2 (0.62) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL669239 0.82 CYP4F2 (0.57) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL6257314 0.80 CYP4F2 (0.85) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL8160235 0.80 CYP4F2 (0.60) CYP4F2CYP4A11MEN1KMT2APKM
SCHEMBL6254544 0.80 CYP4F2 (0.85) CYP4F2CYP4A11MEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3946460-B1 IMPROVED CONJUGATION LINKERS PROLYNX LLC (US) 2026-05-20 EP disclosed
US-20260007768-A1 CONJUGATION LINKERS PROLYNX LLC (US) 2026-01-08 US disclosed
US-12472261-B2 Conjugated inhibitors of DNA damage response PROLYNX LLC (US) 2025-11-18 US disclosed
US-12364771-B2 Conjugation linkers PROLYNX LLC (US) 2025-07-22 US disclosed
CN-119970617-A Improved coupling joint 普罗林科斯有限责任公司 2025-05-13 CN disclosed
US-20240041982-A1 EXTENDED RELEASE HYDROGEL CONJUGATES OF C-NATRIURETIC PEPTIDES PROLYNX LLC (US) 2024-02-08 US disclosed
EP-4251150-A1 EXTENDED RELEASE HYDROGEL CONJUGATES OF C-NATRIURETIC PEPTIDES Prolynx LLC (US) 2023-10-04 EP disclosed
CN-116635027-A Prolonged release hydrogel conjugates of C-natriuretic peptides 普罗林科斯有限责任公司 2023-08-22 CN disclosed
US-20220331437-A1 CONJUGATED INHIBITORS OF DNA DAMAGE RESPONSE PROLYNX LLC (US) 2022-10-20 US disclosed
US-20220280654-A1 IMPROVED CONJUGATION LINKERS PROLYNX LLC (US) 2022-09-08 US disclosed
EP-0562440-B1 Imidazopyridazines as antiasthmatics TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-12-23 EP disclosed
US-5491145-A ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-13 US disclosed
US-5482939-A ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-01-09 US disclosed
US-5476848-A Antihistamines SANKYO COMPANY, LIMITED (JP) 1995-12-19 US disclosed
US-5407933-A Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities and their use SANKYO COMPANY, LIMITED (JP) 1995-04-18 US disclosed
US-5389633-A ANTIASTHMATIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
EP-0562439-A1 Triazolopyridazines as antioasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed
EP-0562440-A1 Imidazopyridazines as antiasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed
CN-1076450-A Nitrogenous tetracyclic compound SANKYO CO (JP) 1993-09-22 CN disclosed
EP-0539164-A1 Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use Sankyo Company Limited (JP) 1993-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220331437-A1 CONJUGATED INHIBITORS OF DNA DAMAGE RESPONSE DCLRE1A, DDB1, RAD50 CYP4F2 3912/4885CYP4A11 4417/4885MEN1 2877/4885
US-20240041982-A1 EXTENDED RELEASE HYDROGEL CONJUGATES OF C-NATRIURETIC PEPTIDES NPPA, NPR1, NPR3 CYP4F2 4571/4885CYP4A11 4470/4885MEN1 1286/4885
US-20220280654-A1 IMPROVED CONJUGATION LINKERS DNPEP, SPPL2B, PTMS CYP4F2 3296/4885CYP4A11 4514/4885MEN1 1057/4885
US-20260007768-A1 CONJUGATION LINKERS OGFR, SLC43A1, ILK CYP4F2 1044/4885CYP4A11 1010/4885MEN1 4764/4885
US-12472261-B2 Conjugated inhibitors of DNA damage response DCLRE1A, DDB1, RAD50 CYP4F2 3912/4885CYP4A11 4417/4885MEN1 2877/4885
US-12364771-B2 Conjugation linkers DNPEP, FGB, VIP CYP4F2 3234/4885CYP4A11 4429/4885MEN1 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.