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Sugi Predict / Compounds / (Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL28205397

C(=Cc1ccccc1)c1ccccc1.NS(=O)(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 3/20 0.52
▸ CYP19A1 P11511 2/20 0.52
▸ MAOA P21397 2/20 0.52
▸ TRPA1 O75762 2/20 0.52
▸ HDAC1 Q13547 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ HDAC3 O15379 1/20 0.50
▸ TNKS O95271 1/20 0.50
▸ HDAC4 P56524 1/20 0.50
▸ HCAR2 Q8TDS4 1/20 0.50
▸ HDAC7 Q8WUI4 1/20 0.50
▸ HDAC2 Q92769 1/20 0.50
▸ HDAC10 Q969S8 1/20 0.50
▸ HDAC11 Q96DB2 1/20 0.50
▸ HDAC8 Q9BY41 1/20 0.50
▸ TNKS2 Q9H2K2 1/20 0.50
▸ HDAC6 Q9UBN7 1/20 0.50
▸ HDAC9 Q9UKV0 1/20 0.50
▸ HDAC5 Q9UQL6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL8520705 0.90 LMNA (0.54) MAOBCYP19A1MAOATRPA1HDAC1
(Z)-1,2-Diphenylethene SCHEMBL8520704 0.90 LMNA (0.54) MAOBCYP19A1MAOATRPA1HDAC1
(Z)-1,2-Diphenylethene SCHEMBL11331699 0.81 LMNA (0.47) MAOBCYP19A1MAOATRPA1HDAC1
(Z)-1,2-Diphenylethene SCHEMBL11331703 0.81 LMNA (0.47) MAOBCYP19A1MAOATRPA1HDAC1
Styrene SCHEMBL1672302 0.81 ALDH1A1 (0.64) HDAC1ALDH1A1LMNAHDAC3TNKS
(Z)-1,2-Diphenylethene SCHEMBL29134000 0.81 MAOB (0.69) MAOBCYP19A1MAOATRPA1HDAC1
SCHEMBL28748742 0.79 TSHR (0.62) MAOBCYP19A1MAOAHDAC1ALDH1A1
(E)-4-Styrylphenol SCHEMBL3991876 0.79 CYP3A4 (0.56) MAOBCYP19A1MAOATRPA1ALDH1A1
SCHEMBL28050659 0.79 CA2 (0.62) MAOBCYP19A1MAOALMNAMAPT
(Z)-1,2-Diphenylethene SCHEMBL28483617 0.79 HDAC1 (0.61) MAOBCYP19A1MAOAHDAC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310623-A Nicotine particles 菲利普莫里斯生产公司 2019-02-05 — — CN disclosed
CN-107667109-A Useful for molecules and biomolecules18Novel F-labelled heteroaromatic silicon fluoride receptor and method for the production thereof 加利福尼亚大学董事会 2018-02-06 — — CN disclosed