Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31107466 | 0.81 | CTRB1 (0.48) | CTRB1ALDH1A1NPSR1CYP2C9MEN1 | |
| SCHEMBL74973 | 0.79 | L3MBTL1 (0.55) | CTRB1CA12CA9ALDH1A1L3MBTL1 | |
| SCHEMBL31241181 | 0.79 | L3MBTL1 (0.55) | CTRB1CA12CA9ALDH1A1L3MBTL1 | |
| SCHEMBL11045402 | 0.78 | ALDH1A1 (0.42) | CA12CA9ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5086855 | 0.75 | CTRB1 (0.70) | CTRB1ALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| Ethylene Glycol SCHEMBL8989789 | 0.75 | L3MBTL1 (0.51) | CTRB1CA12CA9ALDH1A1NPSR1 | |
| SCHEMBL8995177 | 0.75 | ALDH1A1 (0.62) | CTRB1ALDH1A1SMN1; SMN2L3MBTL1ASAH1 | |
| SCHEMBL10768629 | 0.73 | NPSR1 (0.63) | CTRB1CA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL19834306 | 0.73 | NPC1 (0.50) | CTRB1CA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL308281 | 0.72 | CA12 (0.44) | CTRB1CA12CA9ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431799-A | 6'-Modified fortimicin compounds | ABBOTT LABORATORIES (US) | 1984-02-14 | — | — | US | disclosed |