Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177419 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL12471113 | 0.79 | L3MBTL1 (0.48) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL11041894 | 0.78 | CTRB1 (0.42) | ALDH1A1CYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL14193248 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP2C9GAASMN1; SMN2 | |
| SCHEMBL8897656 | 0.76 | CTRB1 (0.51) | ALDH1A1CYP1A2CYP2C9MEN1MAPT | |
| SCHEMBL426217 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL29212757 | 0.74 | ELANE (0.50) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL31712159 | 0.74 | GAA (0.47) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL5712625 | 0.73 | CHRM2 (0.40) | ALDH1A1 | |
| SCHEMBL4355574 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431799-A | 6'-Modified fortimicin compounds | ABBOTT LABORATORIES (US) | 1984-02-14 | — | — | US | disclosed |
| US-4337335-A | Transition metal salt complexes of polyamino organic compounds | SCHERING CORPORATION (US) | 1982-06-29 | — | — | US | disclosed |
| US-4230847-A | Aminoglycoside antibiotic compounds | SCHERING CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4212859-A | OXIMINATION OF AMINO PRECURSOR, ACID HYDROLYSIS, REDUCTION OF OXO GROUP | SCHERING CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0000473-A1 | Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives | Technobiotic Ltd. (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4136254-A | PROCESS OF SELECTIVELY BLOCKING AMINO FUNCTIONS IN AMINOGLYCOSIDES USING TRANSITION METAL SALTS AND INTERMEDIATES USED THEREBY | SCHERING CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |