SCHEMBL5086855

SCHEMBL5086855

O=C(OCc1ccccc1)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.70
P2RX4 Q99571 3/20 0.62
P2RX1 P51575 1/20 0.56
P2RX3 P56373 1/20 0.56
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAPK1 P28482 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
NPC1 O15118 4/20 0.48
RAB9A P51151 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CDC25B P30305 1/20 0.48
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
ASAH1 Q13510 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25583410 0.88 CTRB1 (0.60) CTRB1P2RX4P2RX1P2RX3ALDH1A1
SCHEMBL20673840 0.83 CTRB1 (1.00) CTRB1P2RX4P2RX1P2RX3ALDH1A1
SCHEMBL19984711 0.81 P2RX4 (0.64) CTRB1P2RX4P2RX1P2RX3ALDH1A1
SCHEMBL31107474 0.81 CTRB1 (0.75) CTRB1P2RX4P2RX1P2RX3ALDH1A1
SCHEMBL7358437 0.80 TMEM97 (0.49) CTRB1P2RX4ALDH1A1KMT2AMEN1
SCHEMBL31241181 0.80 L3MBTL1 (0.55) CTRB1ALDH1A1KMT2AL3MBTL1MAPT
SCHEMBL74973 0.80 L3MBTL1 (0.55) CTRB1ALDH1A1KMT2AL3MBTL1MAPT
SCHEMBL274967 0.79 P2RX4 (0.58) CTRB1P2RX4P2RX1P2RX3ALDH1A1
SCHEMBL11209614 0.77 ALDH1A1 (0.54) CTRB1ALDH1A1MAPK1L3MBTL1TDP1
SCHEMBL8897656 0.77 CTRB1 (0.51) CTRB1P2RX4ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374312-A1 COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION COMPRISING SAME, PHOTOSENSITIVE RESIN FILM, COLOR FILTER AND CMOS IMAGE SENSOR SAMSUNG SDI CO., LTD. (KR) 2023-11-23 US disclosed
CN-101405000-A 2-imino-benzimidazoles ABBOTT LAB (US) 2009-04-08 CN disclosed
EP-1983992-A2 2-IMINO-BENZIMIDAZOLES Abbott Laboratories (US) 2008-10-29 EP disclosed
US-20070232673-A1 2-Imino-benzimidazoles ABBOTT LABORATORIES 2007-10-04 US disclosed
WO-2007084728-A2 2-IMINO-BENZIMIDAZOLES ABBOTT LABORATORIES (US) 2007-07-26 WO disclosed
US-6998491-B2 Catalyst comprising a cyclic imide compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-02-14 US disclosed
US-20020128149-A1 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232673-A1 2-Imino-benzimidazoles CYP2C19, UGT2B7, UGT2B17 CTRB1 3662/4885P2RX4 2743/4885P2RX1 2834/4885
US-20020128149-A1 Catalyst comprising a cyclic imide compound and process for producing organic compounds using the catalyst NOX4, POR, NOX1 CTRB1 1356/4885P2RX4 435/4885P2RX1 884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.