Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040669 | 0.78 | IDO1 (0.47) | ALDH1A1LMNAIDO1MAPTGAA | |
| SCHEMBL29893526 | 0.72 | KDM4E (0.42) | ALDH1A1MAPK1LMNAHSD17B10MAPT | |
| SCHEMBL1973786 | 0.66 | NOS3 (0.52) | ALDH1A1MAPK1LMNAPBRM1MAPT | |
| SCHEMBL2515396 | 0.64 | MAOA (0.32) | MAPK1LMNAIDO1MAPTGAA | |
| SCHEMBL358976 | 0.63 | ALDH1A1 (0.67) | ALDH1A1MAPK1LMNAHSD17B10PBRM1 | |
| SCHEMBL31295703 | 0.63 | ALDH1A1 (0.67) | ALDH1A1MAPK1LMNAHSD17B10PBRM1 | |
| SCHEMBL2908519 | 0.61 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL31465796 | 0.61 | ALDH1A1 (0.63) | ALDH1A1MAPK1LMNAHSD17B10PBRM1 | |
| SCHEMBL7519287 | 0.61 | ALDH1A1 (0.63) | ALDH1A1MAPK1LMNAHSD17B10PBRM1 | |
| SCHEMBL2323955 | 0.60 | CHRNB4 (0.47) | ALDH1A1MAPK1LMNAPBRM1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041242-B1 | CARBAMOYLOXYAMINO-1,4-BENZODIAZEPINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-11 | — | — | EP | disclosed |