SCHEMBL11043799

SCHEMBL11043799

Cc1cc(C(F)(C(F)F)C(F)(F)F)cc(C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PTGS1 P23219 11/20 0.38
PTGS2 P35354 11/20 0.38
ALOX5 P09917 8/20 0.36
CYP2C9 P11712 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2B6 P20813 1/20 0.34
TTR P02766 1/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EEF2K O00418 1/20 0.32
SRC P12931 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28429155 0.84 SHBG (0.46) ESR1ESR2CYP2C9CYP1A2CYP2D6
SCHEMBL7606344 0.79 CYP3A4 (0.38) CYP3A4
SCHEMBL28309015 0.79 PDE2A (0.31)
SCHEMBL7461094 0.79
SCHEMBL23174685 0.79 ESR1 (0.52) ESR1ESR2
SCHEMBL28065977 0.78 PGK1 (0.36)
SCHEMBL23174661 0.78 TSHR (0.47) CA1CA2CYP2C9CYP1A2CYP3A4
SCHEMBL4004120 0.75 ALDH1A1 (0.33) MAPT
SCHEMBL21253171 0.73
SCHEMBL29118166 0.73 CES2 (0.38) PTGS1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110888301-B Photosensitive resin composition for light-shielding film, light-shielding film formed by hardening same, and color filter 日铁化学材料株式会社 2023-08-15 CN disclosed
CN-111432917-B Membrane fabrication using co-solvents in polymer dope solution 杜邦安全与建筑公司 2022-06-03 CN disclosed
CN-114555549-A Powder, method for producing powder, and method for producing solution 中央硝子株式会社 2022-05-27 CN disclosed
CN-108025263-B Method for preparing a membrane using a lactam-based solvent 巴斯夫欧洲公司 2021-12-21 CN disclosed
CN-108779252-B Desalting of polyaryl ethers by melt extraction 巴斯夫欧洲公司 2021-08-20 CN disclosed
EP-3841149-A1 METHOD FOR PRODUCING AROMATIC POLYETHERSULFONES CONTAINING ISOHEXIDE ROQUETTE FRERES (FR) 2021-06-30 EP disclosed
CN-107428932-B Desalting of polyaryl ethers by melt extraction 巴斯夫欧洲公司 2021-06-01 CN disclosed
CN-112673052-A Polyarylene ether sulfones 巴斯夫欧洲公司 2021-04-16 CN disclosed
CN-112673051-A Poly (arylene ether) 巴斯夫欧洲公司 2021-04-16 CN disclosed
CN-112673049-A Poly (arylene ether) copolymer 巴斯夫欧洲公司 2021-04-16 CN disclosed
WO-2021065653-A1 POWDER, POWDER PRODUCTION METHOD, AND SOLUTION PRODUCTION METHOD セントラル硝子株式会社 2021-04-08 WO disclosed
CN-111770786-A Removal of metal ions with membranes based on anionic polyarylene ether sulfones and cationic polymers with amino groups 杜邦安全与建筑公司 2020-10-13 CN disclosed
CN-105929642-B Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member 佳能株式会社 2020-09-01 CN disclosed
CN-111432917-A Membrane fabrication using co-solvents in polymer dope solution 杜邦安全与建筑公司 2020-07-17 CN disclosed
CN-106659982-B Method for producing film 巴斯夫欧洲公司 2020-06-26 CN disclosed
WO-2020039127-A1 METHOD FOR PRODUCING AROMATIC POLYETHERSULFONES CONTAINING ISOHEXIDE ROQUETTE FRERES (FR) 2020-02-27 WO disclosed
CN-103969948-B Touch panel black photosensitive composition and touch panel 日铁化学材料株式会社 2019-10-01 CN disclosed
EP-3433300-A1 DESALINATION OF POLYARYL ETHERS BY MEANS OF MELT EXTRACTION BASF SE (DE) 2019-01-30 EP disclosed
EP-0155517-A2 Polyester composition and process for producing shaped articles using same KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-09-25 EP disclosed
US-4199597-A Omega-(4-polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio)alkanoic acids and compounds related thereto SCHERING CORPORATION (US) 1980-04-22 US disclosed