SCHEMBL11043925

SCHEMBL11043925

C[Sn](C)(C)CCCNC(=O)NS(=O)(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 13/20 0.57
CYP2C9 P11712 2/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
TSHR P16473 2/20 0.55
ALB P02768 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
CYP3A4 P08684 1/20 0.49
THRB P10828 1/20 0.49
NFKB1 P19838 1/20 0.49
HTR2A P28223 1/20 0.49
CYP2C19 P33261 1/20 0.49
ADRA1A P35348 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5931108 0.85 FBP1 (0.70) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL184964 0.84 CYP2C9 (0.76) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL11049679 0.82 CYP2C9 (0.69) FBP1CYP2C9ALDH1A1LMNATSHR
Methyl Alcohol SCHEMBL28260710 0.82 CYP2C9 (0.74) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL28534045 0.81 EPHX2 (0.68) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL19271872 0.81 EPHX2 (0.68) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL2290886 0.80 ALDH1A1 (0.72) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL13355486 0.80 MAPK1 (0.64) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL26983176 0.77 CA12 (0.63) FBP1CYP2C9ALDH1A1LMNATSHR
SCHEMBL4923123 0.77 LMNA (0.61) FBP1CYP2C9ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4456559-A Pesticidal N-(3-trimethylstannylalkylene)-N'-phenyl-sulfonyl or -benzoyl-ureas CIBA-GEIGY CORPORATION (US) 1984-06-26 US disclosed