Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | FBP1 | P09467 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931108 | 0.85 | FBP1 (0.70) | CA12CA1CA2CA9FBP1 | |
| SCHEMBL2290886 | 0.83 | ALDH1A1 (0.72) | CA12CA1CA2CA9FBP1 | |
| SCHEMBL21780200 | 0.82 | KDM4E (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL184964 | 0.81 | CYP2C9 (0.76) | CA12CA1CA2CA9FBP1 | |
| SCHEMBL6012074 | 0.80 | CA2 (0.60) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11049679 | 0.80 | CYP2C9 (0.69) | FBP1ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL16158153 | 0.80 | LARS1 (0.57) | CA12CA1CA2CA9FBP1 | |
| Methyl Alcohol SCHEMBL28260710 | 0.80 | CYP2C9 (0.74) | CA12CA1CA2CA9FBP1 | |
| SCHEMBL10607611 | 0.79 | KDM4E (0.68) | CA12CA1CA2CA9FBP1 | |
| SCHEMBL28534045 | 0.78 | EPHX2 (0.68) | FBP1ALDH1A1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240011034-A1 | INHIBITION OF miR-29b-3p TO ENHANCE NEURONAL SURVIVAL IN HUNTINGTON'S DISEASE | WASHINGTON UNIVERSITY | 2024-01-11 | — | — | US | disclosed |