SCHEMBL11045977

SCHEMBL11045977

C1=CC2(COC(OCC34C=CC(CC3)C4)c3ccccc3)CCC1C2

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
ADRA2A P08913 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
TSHR P16473 1/20 0.30
ADRA2B P18089 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HRH2 P25021 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
OPRM1 P35372 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10700252 0.78 TDP1 (0.34) SLC6A2SLC6A4ADRA1ASLC6A3
SCHEMBL9722061 0.72
SCHEMBL443563 0.72 MAOA (0.40) LMNAOPRM1OPRK1
SCHEMBL17912773 0.70 KCNA3 (0.39) ADRA1ADRD3
SCHEMBL15063657 0.69 ALDH1A1 (0.34) LMNATSHR
SCHEMBL20362170 0.67 OPRM1 (0.36) CYP1A2CYP2D6TSHROPRM1
SCHEMBL9792899 0.67 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL7120876 0.66
SCHEMBL7930112 0.64
SCHEMBL960448 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0062809-B1 USE OF NON-CYCLIC ACETALS OR KETALS AS NON-DISCOLOURING ANTIOZONANTS BAYER AG (DE) 1984-05-23 EP disclosed
US-4427817-A Open-chain acetals or ketals as non-discoloring antiozonants for rubber BAYER AKTIENGESELLSCHAFT (DE) 1984-01-24 US disclosed
EP-0062809-A1 Use of non-cyclic acetals or ketals as non-discolouring antiozonants BAYER AG (DE) 1982-10-20 EP disclosed