Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046086 | 0.88 | ALDH1A1 (0.53) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL11047148 | 0.88 | MAOA (0.63) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL17193484 | 0.84 | TP53 (0.81) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL20804375 | 0.78 | SMN1; SMN2 (0.85) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL11048822 | 0.77 | MEN1 (0.71) | TP53SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL7098404 | 0.77 | TP53 (0.68) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL10904255 | 0.77 | SIRT1 (0.58) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL11431155 | 0.76 | MAOA (0.56) | TP53SMN1; SMN2EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL133103 | 0.75 | SMN1; SMN2 (1.00) | SIRT1TP53SMN1; SMN2EPHX1TSHR | |
| SCHEMBL19501805 | 0.75 | KMT2A (0.81) | SIRT1TP53SMN1; SMN2EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481285-A | IMPROVED SHAPPNESS AND EDGE EFFECTS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-06 | — | — | US | disclosed |