Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685381 | 0.97 | LTA4H (0.46) | LTA4HPTGS2MRGPRX1CYP3A4ESRRA | |
| SCHEMBL11521654 | 0.86 | LTA4H (0.58) | LTA4HPTGS2MRGPRX1RXRARXRB | |
| SCHEMBL1339067 | 0.85 | KDM4E (0.52) | LTA4HPTGS2MRGPRX1CYP3A4RXRA | |
| SCHEMBL10368048 | 0.85 | RXRA (0.41) | LTA4HPTGS2MRGPRX1CYP3A4ESRRA | |
| SCHEMBL21858138 | 0.85 | L3MBTL1 (0.47) | LTA4HPTGS2MRGPRX1CYP3A4ESRRA | |
| SCHEMBL10902334 | 0.85 | AR (0.53) | LTA4HPTGS2MRGPRX1CYP3A4ESRRA | |
| SCHEMBL11144791 | 0.85 | LTA4H (0.40) | LTA4HPTGS2MRGPRX1CYP3A4ESRRA | |
| SCHEMBL5379995 | 0.85 | AR (0.53) | LTA4HPTGS2MRGPRX1RXRARXRB | |
| SCHEMBL1676646 | 0.84 | LTA4H (0.53) | LTA4HPTGS2MRGPRX1RXRARXRB | |
| SCHEMBL946862 | 0.83 | AR (0.41) | LTA4HPTGS2MRGPRX1CYP3A4ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450308-A | Process for the preparation of trifluoromethylphenyl oxyphenyl ether compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |
| US-4450308-A | Process for the preparation of trifluoromethylphenyl oxyphenyl ether compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |
| US-4450308-A | Process for the preparation of trifluoromethylphenyl oxyphenyl ether compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |