Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685381 | 0.87 | LTA4H (0.46) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL11048002 | 0.85 | LTA4H (0.45) | ARTHRATHRBRXRARXRB | |
| SCHEMBL27886587 | 0.83 | AR (0.49) | ARTHRATHRBTSHRCA1 | |
| SCHEMBL69460 | 0.80 | ALDH1A1 (0.56) | ARTSHRCA1CA2TP53 | |
| SCHEMBL29492110 | 0.80 | ALDH1A1 (0.56) | ARTSHRCA1CA2TP53 | |
| Water SCHEMBL29062667 | 0.80 | AR (0.47) | ARTHRATHRBTSHRCA1 | |
| SCHEMBL6061860 | 0.80 | ALDH1A1 (0.59) | ARTSHRCA1CA2TP53 | |
| SCHEMBL29446988 | 0.80 | CA2 (0.62) | ARTSHRCA1CA2TP53 | |
| SCHEMBL18197 | 0.80 | CA2 (0.62) | ARTSHRCA1CA2TP53 | |
| Potassium SCHEMBL29898272 | 0.78 | ALDH1A1 (0.54) | ARTSHRCA2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| EP-0009871-A1 | Organic phosphoric acid ester derivatives, a process for preparing the same and fungicidal, insecticidal or miticidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1980-04-16 | — | — | EP | claimed |
| JP-55154931-A | — | — | None | — | — | JP | disclosed |
| JP-55153794-A | — | — | None | — | — | JP | disclosed |
| JP-55072199-A | — | — | None | — | — | JP | disclosed |
| JP-55108849-A | — | — | None | — | — | JP | disclosed |
| JP-54109934-A | — | — | None | — | — | JP | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| US-5219477-A | Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |
| JP-S55154931-A | TRIFLUOROMETHYLPHENOXYISOPROPYLBENZENE AND ITS PREPARATION | IHARA CHEM IND CO LTD | 1980-12-02 | — | — | JP | disclosed |
| JP-S55153794-A | ORGANIC PHOSPHORIC ESTER DERIVATIVE, ITS PREPARATION, AND GERMICIDE, INSECTICIDE, AND ACARICIDE COMPRISING IT | KUMIAI CHEM IND CO LTD | 1980-11-29 | — | — | JP | disclosed |
| JP-S55108849-A | TRIFLUOROMETHYLPHENOXYCUMENEHYDROPEROXIDE AND ITS PREPARATION | IHARA CHEM IND CO LTD | 1980-08-21 | — | — | JP | disclosed |
| JP-S5572199-A | ORGANIC PHOSPHATE DERIVATIVE, ITS PREPARATION, AND INSECTICIDE AND ACARICIDE COMPRISING IT | KUMIAI CHEM IND CO LTD | 1980-05-30 | — | — | JP | disclosed |
| EP-0009871-A1 | Organic phosphoric acid ester derivatives, a process for preparing the same and fungicidal, insecticidal or miticidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |
| EP-0009871-A1 | Organic phosphoric acid ester derivatives, a process for preparing the same and fungicidal, insecticidal or miticidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |
| JP-S54109934-A | PHENOXYPHENOXYCROTONIC ACID, ITS PREPARATION, AND HERBICIDES CONTAINING IT | KUMIAI CHEM IND CO LTD | 1979-08-29 | — | — | JP | disclosed |
| US-4163661-A | Phenoxyphenoxy crotonic acid derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | AR 129/4885THRA 144/4885THRB 119/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | AR 93/4885THRA 115/4885THRB 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.