Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | CBS | P35520 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590939 | 0.79 | ALOX15 (0.41) | TSHRTHRBSMN1; SMN2 | |
| SCHEMBL3861981 | 0.74 | — | — | |
| SCHEMBL28262576 | 0.74 | — | — | |
| SCHEMBL3874819 | 0.74 | — | — | |
| SCHEMBL2241969 | 0.74 | — | — | |
| SCHEMBL3874816 | 0.74 | — | — | |
| SCHEMBL9866275 | 0.73 | PRKCA (0.42) | TSHRCTHCBSTHPOTHRB | |
| Hydrochloric Acid SCHEMBL5498424 | 0.72 | TSHR (0.37) | TSHR | |
| SCHEMBL14879624 | 0.71 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL22926635 | 0.71 | KDM4E (0.40) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447356-A | CYCLIC POLYPEPTIDES; MOLLUSC VENOMS; ANTICHOLINERGIC AGENTS; NERVOUS SYSTEM DISORDERS | OLIVERA BALDOMERO M | 1984-05-08 | — | — | US | disclosed |