Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039561 | 0.88 | METAP2 (0.47) | METAP2RAB9ASMN1; SMN2CA12ALPL | |
| SCHEMBL11047835 | 0.83 | METAP2 (0.38) | METAP2RAB9ASMN1; SMN2ALPLNPC1 | |
| SCHEMBL7487071 | 0.80 | ADORA3 (0.41) | MAPTKDM4EALDH1A1GAANISCH | |
| SCHEMBL11048397 | 0.80 | PDGFRB (0.47) | RAB9ASMN1; SMN2ALPLCA9NPC1 | |
| SCHEMBL15818572 | 0.79 | MAPK1 (0.38) | RAB9ASMN1; SMN2CA12ALPLNPC1 | |
| SCHEMBL11049905 | 0.79 | NOTUM (0.47) | METAP2CA12ALPLMEN1KMT2A | |
| SCHEMBL855275 | 0.79 | METAP2 (0.38) | METAP2RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL4878975 | 0.79 | NOTUM (0.44) | RAB9ASMN1; SMN2ALPLLMNAMEN1 | |
| SCHEMBL11049642 | 0.77 | ALPL (0.42) | RAB9ASMN1; SMN2ALPLCA9NPC1 | |
| SCHEMBL4039334 | 0.76 | RAB9A (0.45) | METAP2RAB9ASMN1; SMN2CA12ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | claimed |
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |