SCHEMBL1104860

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1104863	0.92	AOC3 (0.56)	MDM2CYP11B2CYP11B1AOC3MAPT
	SCHEMBL1104858	0.90	MDM2 (0.59)	MDM2ATMAOC3ALOX12GSR
	SCHEMBL1104842	0.87	ESR1 (0.55)	MAPTKDM4ENPC1ALDH1A1TP53
	SCHEMBL1104839	0.85	ALDH1A1 (0.58)	MDM2ATMAOC3GSRMAPT
	SCHEMBL1104864	0.85	ALDH1A1 (0.54)	MDM2ATMAOC3MAPTKDM4E
	SCHEMBL19986452	0.84	MDM2 (0.45)	MDM2CYP11B2CYP11B1ALOX12GSR
	SCHEMBL1104853	0.82	AOC3 (0.53)	MDM2CYP11B2CYP11B1AOC3MAPT
	SCHEMBL24811940	0.80	MDM2 (0.52)	MDM2ATMCYP11B2CYP11B1AOC3
	SCHEMBL15081862	0.79	GSR (0.56)	MDM2CYP11B2CYP11B1AOC3ALOX12
	SCHEMBL22522226	0.79	MDM2 (0.56)	MDM2ATMCYP11B2AOC3ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.