SCHEMBL1104853

SCHEMBL1104853

Cc1ccc2c(c1)nc(-c1cccnc1)n2-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.53
DHFR P00374 1/20 0.51
MAPT P10636 7/20 0.50
MDM2 Q00987 1/20 0.50
PDE10A Q9Y233 3/20 0.49
G6PD P11413 1/20 0.49
NLRP3 Q96P20 1/20 0.49
SIRT2 Q8IXJ6 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104858 0.92 MDM2 (0.59) AOC3DHFRMAPTMDM2PDE10A
SCHEMBL1104863 0.90 AOC3 (0.56) AOC3DHFRMAPTMDM2G6PD
SCHEMBL1104831 0.87 NLRP3 (0.61) PDE10ANLRP3SIRT2SIRT1ALDH1A1
SCHEMBL1104848 0.85 ALDH1A1 (0.58) AOC3DHFRMAPTMDM2PDE10A
SCHEMBL1104845 0.85 ALDH1A1 (0.54) AOC3DHFRMAPTMDM2PDE10A
SCHEMBL540960 0.85 AOC3 (0.63) AOC3MAPTMDM2G6PDMEN1
SCHEMBL13486686 0.84 SIRT2 (0.62) PDE10ANLRP3SIRT2SIRT1ALDH1A1
SCHEMBL10979856 0.83 NLRP3 (0.60) PDE10ANLRP3SIRT2SIRT1ALDH1A1
SCHEMBL1104860 0.82 MDM2 (0.59) AOC3DHFRMAPTMDM2NLRP3
SCHEMBL19884345 0.81 MAPK1 (0.55) PDE10ANLRP3SIRT2SIRT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-12-22 US disclosed
US-11189809-B2 Organic EL device and display unit SONY CORPORATION (JP) 2021-11-30 US disclosed
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
US-10411212-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-09-10 US disclosed
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-17 US disclosed
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-17 US disclosed
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-10 US disclosed
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-10 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-20090009066-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090009066-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090009065-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090009065-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080258613-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-10-23 US disclosed
US-20080258613-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-10-23 US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090009065-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, RFT1, RAE1 AOC3 901/4885DHFR 4461/4885MAPT 2311/4885
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX AOC3 447/4885DHFR 2840/4885MAPT 792/4885
US-10411212-B2 Organic electroluminescent element L1CAM, NES, EML4 AOC3 192/4885DHFR 4635/4885MAPT 1534/4885
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME PPOX, EPCAM, STOM AOC3 465/4885DHFR 3018/4885MAPT 712/4885
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same PPOX, EPCAM, STOM AOC3 465/4885DHFR 3018/4885MAPT 712/4885
US-11189809-B2 Organic EL device and display unit L1CAM, ESR1, EPHA8 AOC3 79/4885DHFR 4744/4885MAPT 2910/4885
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX AOC3 447/4885DHFR 2840/4885MAPT 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.