Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887988 | 1.00 | MAPT (0.57) | MAPTALDH1A1POLBESR1NR4A1 | |
| SCHEMBL21510835 | 0.90 | CA2 (0.55) | MAPTESR1ESR2KMT2ACA2 | |
| SCHEMBL9820117 | 0.90 | ALDH1A1 (0.59) | MAPTALDH1A1POLBESR1NR4A1 | |
| SCHEMBL11048869 | 0.90 | CA2 (0.55) | MAPTESR1ESR2KMT2ACA2 | |
| SCHEMBL18531405 | 0.83 | ALDH1A1 (0.52) | MAPTALDH1A1POLBESR1NR4A1 | |
| SCHEMBL26253885 | 0.83 | MAPT (0.55) | MAPTALDH1A1POLBESR1NR4A1 | |
| SCHEMBL27773636 | 0.82 | KMT2A (0.66) | ALDH1A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20002876 | 0.81 | ACHE (0.58) | MAPTALDH1A1POLBESR1NR4A1 | |
| SCHEMBL2922447 | 0.81 | POLB (0.49) | MAPTPOLBESR1ESR2CTDSP1 | |
| SCHEMBL29937971 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1POLBESR1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589020-B1 | NOVEL COMPOUNDS CAPABLE OF FORMING PHOTOCONVERTIBLE ORGANIC THIN FILMS AND ARTICLES HAVING ORGANIC THIN FILMS | NIPPON SODA CO (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-7855281-B2 | Cleavable thiocarbonate linkers for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| US-7572908-B2 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7470803-B2 | Compounds for forming photoconvertible organic thin film and organic thin film formed body | NIPPON SODA CO., LTD. (JP) | 2008-12-30 | — | — | US | disclosed |
| US-20070224603-A1 | Cleavable linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070224602-A1 | Thiocarbonate linkers for polynucleotides | AGILENT TECHNOLOGIES, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20060138400-A1 | Novel compounds capable of forming photoconvertible organic thin film and articles having organic thin film | NIPPON SODA CO.,LTD. (JP) | 2006-06-29 | — | — | US | disclosed |
| EP-1589020-A1 | NOVEL COMPOUNDS CAPABLE OF FORMING PHOTOCONVERTIBLE ORGANIC THIN FILMS AND ARTICLES HAVING ORGANIC THIN FILMS | NIPPON SODA CO., LTD. (JP) | 2005-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224603-A1 | Cleavable linkers for polynucleotides | PNKP, PCNA, TYMP | MAPT 3108/4885ALDH1A1 4159/4885POLB 63/4885 |
| US-20070224602-A1 | Thiocarbonate linkers for polynucleotides | TYMP, DTYMK, RNGTT | MAPT 3654/4885ALDH1A1 4003/4885POLB 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.