SCHEMBL11048904

SCHEMBL11048904

C=CC(Oc1cccc(OCCC=O)c1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
ATM Q13315 1/20 0.41
NSD2 O96028 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
THRB P10828 1/20 0.38
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
LMNA P02545 2/20 0.37
RAB9A P51151 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625768 0.81 PTGIR (0.41) KMT2ASMN1; SMN2PTGDR2
SCHEMBL16672084 0.79 MAPK1 (0.42) KDM4EALDH1A1L3MBTL1KMT2ANSD2
SCHEMBL8625006 0.76 MAOA (0.49) ALDH1A1L3MBTL1KMT2ATDP1MEN1
SCHEMBL3295618 0.75 MAOB (0.44) KDM4EALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL43677 0.74 KCNA3 (0.58) ALDH1A1THRBHTR1DHTR1B
SCHEMBL3291158 0.74 SLC6A4 (0.39) KDM4EALDH1A1
SCHEMBL3293320 0.73 RXRA (0.46)
SCHEMBL5254178 0.73 LTA4H (0.53)
SCHEMBL19287147 0.71 MAPK1 (0.56) KDM4EALDH1A1L3MBTL1KMT2ATDP1
SCHEMBL11048902 0.70 NPC1 (0.42) KDM4EALDH1A1L3MBTL1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478992-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1984-10-23 US disclosed
US-4420630-A BINDERS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed
US-4335254-A Polymerizable acryloyloxyarylenesulfonamides EASTMAN KODAK COMPANY (US) 1982-06-15 US disclosed
US-4289865-A USEFUL IN RELIEF IMAGES OR AS BINDERS IN PHOTOGRAPHIC MATERIALS EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
US-4281207-A CROSSLINKING POLYMERS USEFUL IN RELIEF IMAGES, PHOTORESISTS, AND LITHOGRAPHIC PLATES EASTMAN KODAK COMPANY (US) 1981-07-28 US disclosed
US-4259469-A DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY EASTMAN KODAK COMPANY (US) 1981-03-31 US disclosed
US-4225689-A PHOTORESISTS, LITHOGRAPHIC PLATES, RELIF IMAGES EASTMAN KODAK COMPANY (US) 1980-09-30 US disclosed