SCHEMBL11048962

SCHEMBL11048962

O=S(=O)(Cl)c1ccc2ccc(S(=O)(=O)Cl)c(Cl)c2c1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.36
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
PARG Q86W56 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CASP6 P55212 1/20 0.32
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11136985 0.78 HTR6 (0.41) ALDH1A1HSD17B10TDP1
SCHEMBL6376676 0.77 CYP2A6 (0.52) ALDH1A1HSD17B10TDP1CYP3A4MAPK1
SCHEMBL2327076 0.76 MAPK1 (0.43) TRPV4ALDH1A1MAPK1
SCHEMBL2196286 0.76 ALDH1A1 (0.40) TRPV4ALDH1A1HSD17B10TDP1CYP2C9
SCHEMBL31387942 0.74 CYP1A2 (0.47) ALDH1A1HSD17B10TDP1CYP2C9CYP2C19
SCHEMBL6181850 0.74 CYP1A2 (0.47) ALDH1A1HSD17B10TDP1CYP2C9CYP2C19
SCHEMBL11427098 0.74 TRPV4 (0.55) TRPV4ALDH1A1HSD17B10TDP1CYP2C9
SCHEMBL29057554 0.73 ALDH1A1 (0.44) TRPV4ALDH1A1HSD17B10TDP1CYP2C9
SCHEMBL6535639 0.73 NR1I2 (0.36) TRPV4ALDH1A1HSD17B10TDP1CYP2C9
SCHEMBL2263563 0.73 LMNA (0.48) ALDH1A1HSD17B10TDP1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4438245-A FOR LIGHT SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-03-20 US disclosed