Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048982 | 0.80 | KDM4E (0.37) | QPCTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL11045232 | 0.76 | ALDH1A1 (0.60) | QPCTSMN1; SMN2ALDH1A1RXFP1NPSR1 | |
| SCHEMBL11045234 | 0.68 | GRIK1 (0.45) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5123935 | 0.68 | QPCT (1.00) | QPCTKDM4EALDH1A1RXFP1 | |
| SCHEMBL11051146 | 0.68 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5125330 | 0.68 | QPCT (1.00) | QPCTKMT2A | |
| SCHEMBL23635683 | 0.64 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1RXFP1NPSR1 | |
| SCHEMBL24961270 | 0.64 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL1993342 | 0.64 | QPCT (0.60) | QPCTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL19265939 | 0.63 | QPCT (0.43) | QPCTSMN1; SMN2ALDH1A1ADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442289-A | ANTIASTHMA | HOFFMANN-LA ROCHE INC. (US) | 1984-04-10 | — | — | US | disclosed |
| US-4376121-A | Antiallerigically-active imidazothienopyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1983-03-08 | — | — | US | disclosed |