Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 4/20 | 0.32 |
| ▸ | MMP8 | P22894 | 4/20 | 0.32 |
| ▸ | MMP12 | P39900 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 4/20 | 0.32 |
| ▸ | MMP14 | P50281 | 4/20 | 0.32 |
| ▸ | MMP16 | P51512 | 4/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044000 | 0.79 | MMP2 (0.40) | MMP2MMP8MMP12MMP13MMP14 | |
| SCHEMBL10646473 | 0.78 | GABRA1 (0.35) | CTSBGABRA1GABRB2 | |
| SCHEMBL8549823 | 0.78 | GABRA1 (0.32) | CTSBGABRA1GABRB2 | |
| SCHEMBL11045411 | 0.77 | GABRA1 (0.33) | CTSBGABRA1GABRB2 | |
| SCHEMBL6677573 | 0.76 | GAA (0.36) | MEN1CYP3A4CYP2C19KMT2AF2 | |
| SCHEMBL1945878 | 0.76 | CYP3A4 (0.37) | CTSBGABRA1GABRB2CYP3A4CYP2D6 | |
| SCHEMBL15150643 | 0.75 | MEN1 (0.49) | CTSBNAMPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL10690933 | 0.75 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL10694395 | 0.75 | TDP1 (0.31) | GABRA1GABRB2TDP1 | |
| SCHEMBL10806335 | 0.75 | KEAP1 (0.34) | MEN1KMT2AF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424377-A | HERBICIDES | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-03 | — | — | US | claimed |
| US-4424377-A | HERBICIDES | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |