SCHEMBL8549823

SCHEMBL8549823

O=C=NS(=O)(=O)c1ccccc1CF

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CTSB P07858 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10646473 0.82 GABRA1 (0.35) GABRA1GABRB2CTSB
SCHEMBL6677573 0.80 GAA (0.36)
SCHEMBL10690933 0.79 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL10694395 0.79 TDP1 (0.31) GABRA1GABRB2
SCHEMBL10383754 0.79 HSD11B1 (0.31)
SCHEMBL11067005 0.78 MMP2 (0.51)
SCHEMBL11045411 0.78 GABRA1 (0.33) GABRA1GABRB2CTSBLMNA
SCHEMBL11049036 0.78 CTSB (0.34) GABRA1GABRB2CTSB
SCHEMBL5268908 0.77 NFE2L2 (0.38)
SCHEMBL31259921 0.77 NFE2L2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828738-A1 PYRIDYL-THIAZOLES AND THEIR USE TO PROTECT PLANTS AGAINST INFECTIONS BY MICRO-ORGANISMS BAYER AG (DE) 1998-03-18 EP disclosed
WO-1996037493-A1 PYRIDYL-THIAZOLES AND THEIR USE TO PROTECT PLANTS AGAINST INFECTIONS BY MICRO-ORGANISMS BAYER AKTIENGESELLSCHAFT (DE) 1996-11-28 WO disclosed