SCHEMBL10690933

SCHEMBL10690933

O=C=NS(=O)(=O)c1ccccc1CCCl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10646473 0.86 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL10694395 0.83 TDP1 (0.31) GABRA1GABRB2
SCHEMBL1945878 0.81 CYP3A4 (0.37) GABRA1GABRB2
SCHEMBL27527586 0.80 LIPG (0.41)
SCHEMBL10383754 0.80 HSD11B1 (0.31)
SCHEMBL8549823 0.79 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL6677573 0.78 GAA (0.36)
SCHEMBL587388 0.76 GAA (0.41)
Cyanide SCHEMBL27388351 0.76 LIPG (0.39)
SCHEMBL11067005 0.75 MMP2 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4770690-A Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
EP-0106512-B1 HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-18 EP disclosed
US-4699650-A Herbicidal ortho-alkyl-and ortho-alkenyl substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-13 US disclosed
US-4678502-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-07 US disclosed
EP-0106512-A2 Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-04-25 EP disclosed