Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046058 | 0.69 | CHRM2 (0.34) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| Bromide SCHEMBL11047588 | 0.68 | CHRM2 (0.33) | HTTMAPTALDH1A1CHRM2CHRM4 | |
| SCHEMBL11048197 | 0.68 | PKM (0.41) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL11291808 | 0.64 | CHRM2 (0.36) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL11043941 | 0.63 | ALDH1A1 (0.36) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27784023 | 0.61 | PKM (0.47) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL11045006 | 0.60 | CTSL (0.43) | ALDH1A1 | |
| SCHEMBL28125148 | 0.60 | PKM (0.58) | PKMKDM4ETHRBHTTMAPT | |
| SCHEMBL14457519 | 0.60 | MAPT (0.43) | KDM4ETHRBHTTMAPTALDH1A1 | |
| SCHEMBL5722381 | 0.58 | PKM (0.39) | PKMKDM4ETHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465844-A | PEPTIDE, GERMICIDE, DISINFECTANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-14 | — | — | US | disclosed |
| US-4436918-A | FROM A 2,5-DIOXOPYRROLIDINE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |