Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 3/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279803 | 0.79 | ACHE (0.33) | TSHRMAPK1TEAD3 | |
| SCHEMBL844941 | 0.77 | TSHR (0.59) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL10626929 | 0.71 | TSHR (0.56) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL31364136 | 0.71 | RAB9A (0.40) | ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL9786661 | 0.69 | TSHR (0.54) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| Ether SCHEMBL8375535 | 0.69 | TSHR (0.48) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| Ethylene Glycol SCHEMBL5904195 | 0.67 | TSHR (0.46) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL34047 | 0.66 | — | — | |
| SCHEMBL28214296 | 0.66 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL251019 | 0.66 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486532-A | IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM | TNANBE SEIYAKU CO., LTD. (JP) | 1984-12-04 | — | — | US | disclosed |