SCHEMBL2279803

SCHEMBL2279803

C=CC(=O)N1CCN(C(=O)C=C)C1=O

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.33
TET3 O43151 2/20 0.33
KMT2A Q03164 2/20 0.33
FBXL19 Q6PCT2 2/20 0.33
CXXC5 Q7LFL8 2/20 0.33
KDM2B Q8NHM5 2/20 0.33
CXXC4 Q9H2H0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
TET1 Q8NFU7 1/20 0.33
PAX8 Q06710 2/20 0.32
MAPK1 P28482 1/20 0.32
TEAD3 Q99594 1/20 0.31
GSK3B P49841 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049984 0.79 ALDH1A1 (0.37) MAPK1TEAD3TSHR
SCHEMBL12764295 0.76
SCHEMBL22122385 0.74 RAB9A (0.35) ACHE
SCHEMBL22122383 0.74 RAB9A (0.35) ACHE
SCHEMBL354728 0.73 NAAA (0.42)
SCHEMBL346131 0.73 LMNA (0.53) KMT2AGSK3BCYP2D6TSHRLMNA
SCHEMBL9802233 0.73 NPSR1 (0.44) ACHETET3KMT2AFBXL19CXXC5
SCHEMBL4362204 0.72 LMNA (0.47) KMT2AMAPK1GSK3BCYP2D6TSHR
SCHEMBL5667561 0.72 LMNA (0.52) KMT2AGSK3BCYP2D6TSHRLMNA
SCHEMBL224075 0.70 LMNA (0.46) KMT2AMAPK1GSK3BCYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200316529-A1 METHOD FOR PRODUCING DN GEL MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-10-08 US claimed
EP-3466987-A1 METHOD FOR PRODUCING DN GEL MEMBRANE Sumitomo Chemical Company Limited (JP) 2019-04-10 EP claimed
EP-0684250-B1 New poly(pentaerythrityl diphosphonate) and its use in self-extinguishing thermoplastic compositions GREAT LAKES CHEMICAL ITALIA (IT) 2000-09-27 EP claimed
US-5597855-A FIREPROOFING ENIRICERCHE S.P.A. (IT) 1997-01-28 US claimed
EP-0684250-A1 New poly(pentaerythrityl diphosphonate) and its use in self-extinguishing termoplastic compositions GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1995-11-29 EP claimed
US-4486532-A IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM TNANBE SEIYAKU CO., LTD. (JP) 1984-12-04 US claimed
US-4081327-A IMMOBILIZED GLUCOSE ISOMERASE-PRODUCING MICROORGANISM TANABE SEIYAKU CO., LTD. (JA) 1978-03-28 US claimed
US-3953291-A IMMOBILIZED ENZYMES TANABE SEIYAKU CO., LTD. (JA) 1976-04-27 US claimed
JP-8120087-A None JP disclosed
US-20230302203-A1 IMPLANT USING NANOCOMPOSITE HYDROGEL GN CORPORATION CO LTD (JP) 2023-09-28 US disclosed
US-20200316529-A1 METHOD FOR PRODUCING DN GEL MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-10-08 US disclosed
EP-3466987-A1 METHOD FOR PRODUCING DN GEL MEMBRANE Sumitomo Chemical Company Limited (JP) 2019-04-10 EP disclosed
US-9162007-B2 Superabsorbent polymer composite comprising a superabsorbent polymer and cellulosic nanofibrils SCA HYGIENE PRODUCTS AB (SE) 2015-10-20 US disclosed
EP-2373352-B1 SUPERABSORBENT POLYMER COMPOSITE COMPRISING A SUPERABSORBENT POLYMER AND CELLULOSIC NANOFIBRILS SCA HYGIENE PROD AB (SE) 2013-11-06 EP disclosed
EP-0115436-A2 Medium for electrophoresis FUJI PHOTO FILM CO., LTD. (JP) 1984-08-08 EP disclosed
US-4081327-A IMMOBILIZED GLUCOSE ISOMERASE-PRODUCING MICROORGANISM TANABE SEIYAKU CO., LTD. (JA) 1978-03-28 US disclosed
US-4081327-A IMMOBILIZED GLUCOSE ISOMERASE-PRODUCING MICROORGANISM TANABE SEIYAKU CO., LTD. (JA) 1978-03-28 US disclosed
US-3953291-A IMMOBILIZED ENZYMES TANABE SEIYAKU CO., LTD. (JA) 1976-04-27 US disclosed
US-3953291-A IMMOBILIZED ENZYMES TANABE SEIYAKU CO., LTD. (JA) 1976-04-27 US disclosed
US-3922195-A Process for preparing L-Malic acid TANABE SEIYAKU CO 1975-11-25 US disclosed