Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052061 | 0.82 | MET (0.49) | MAPTL3MBTL1 | |
| SCHEMBL913813 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAALOX12 | |
| Methane SCHEMBL27598399 | 0.77 | MEN1 (0.97) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL11048969 | 0.75 | KDM4E (0.57) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL11048463 | 0.74 | MET (0.43) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL11044512 | 0.74 | L3MBTL1 (0.46) | KMT2AALDH1A1POLBL3MBTL1 | |
| SCHEMBL5800553 | 0.73 | MEN1 (0.73) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL20303457 | 0.73 | KMT2A (0.64) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL2393208 | 0.71 | MAPT (0.68) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL11049173 | 0.70 | HDAC6 (0.45) | KMT2ALMNARAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477664-A | CARCINOSTATIC ACTIVITY, LOW TOXICITY, INTERMEDIATES | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4477666-A | ANTICARCINO GENIC AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4460774-A | ANTICARCINOGENIC AGENTS | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4448963-A | ANTICARCINOGENS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4436921-A | CARCINOSTATIC ACTIVITY | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |