Resorcin Brown

Resorcin Brown

SCHEMBL109260

Cc1ccc(/N=N/c2c(O)ccc(/N=N/c3ccc(S(=O)(=O)[O-])cc3)c2O)c(C)c1.[Na+]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Resorcin Brown. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 3/20 0.53
MAPK1 P28482 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HIF1A Q16665 2/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
RECQL P46063 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
PLCG1 P19174 1/20 0.47
PTPN1 P18031 4/20 0.47
USP2 O75604 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcin Brown SCHEMBL185545 1.00 THRB (0.53) THRBMAPK1TDP1ALDH1A1HIF1A
Resorcin Brown SCHEMBL110507 0.89 RPS6KA3 (0.59) THRBMAPK1TDP1ALDH1A1HIF1A
Resorcin Brown SCHEMBL31650975 0.89 RPS6KA3 (0.59) THRBMAPK1TDP1ALDH1A1HIF1A
Resorcin Brown SCHEMBL110506 0.89 RPS6KA3 (0.59) THRBMAPK1TDP1ALDH1A1HIF1A
Resorcin Brown SCHEMBL185544 0.88 RPS6KA3 (0.57) THRBMAPK1TDP1ALDH1A1HIF1A
Resorcin Brown SCHEMBL185546 0.88 RPS6KA3 (0.57) THRBMAPK1TDP1ALDH1A1HIF1A
SCHEMBL8946891 0.86 NPC1 (0.61) THRBMAPK1TDP1ALDH1A1HIF1A
SCHEMBL19958473 0.83 NPC1 (0.69) THRBMAPK1TDP1ALDH1A1HIF1A
SCHEMBL1567479 0.82 FTO (0.61) THRBMAPK1TDP1ALDH1A1HIF1A
SCHEMBL5351766 0.75 RPS6KA3 (0.59) THRBMAPK1TDP1ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1901 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701618-A1 METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF A SHAMPOO Henkel AG & Co. KGaA (DE) 2026-03-04 EP claimed
EP-4701617-A1 METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF AN AFTERTREATMENT AGENT CONTAINING PROTEIN HYDROLYSATE AND/OR AMINO ACID Henkel AG & Co. KGaA (DE) 2026-03-04 EP claimed
EP-4452210-B1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KAO CORP (JP) 2026-01-14 EP claimed
EP-3723864-B1 THICKENED ONE-COMPONENT HAIR TONER HENKEL AG & CO KGAA (DE) 2026-01-14 EP claimed
EP-4398865-B1 MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER OREAL (FR) 2025-10-29 EP claimed
US-12383480-B2 Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof KAO CORPORATION (JP) 2025-08-12 US claimed
EP-3873416-B1 METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER HENKEL AG & CO KGAA (DE) 2025-02-26 EP claimed
EP-3873402-B1 METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER HENKEL AG & CO KGAA (DE) 2025-02-26 EP claimed
WO-2025036900-A1 HAIR DYEING COMPOSITION KAO CORPORATION (JP) 2025-02-20 WO claimed
US-20250041181-A1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KAO CORPORATION (JP) 2025-02-06 US claimed
EP-0589656-B1 Method of coloring hair with water soluble acid dyes DOW CORNING (US) 1997-05-14 EP claimed
EP-0684463-A1 Temperature indicating device and composition for use therein PyMaH Corporation (US) 1995-11-29 EP claimed
US-5401100-A Axillary thermometer packaging PYMAH CORPORATION (US) 1995-03-28 US claimed
EP-0589656-A2 Method of coloring hair with water soluble acid dyes DOW CORNING CORPORATION (US) 1994-03-30 EP claimed
US-5281240-A Temporary color which does not stain skin, cationic silicon compounds DOW CORNING CORPORATION (US) 1994-01-25 US claimed
US-5094545-A Solid solution with nucleating agent and indicator dye PYMA CORPORATION (US) 1992-03-10 US claimed
US-4362645-A Temperature indicating compositions of matter AKZONA, INC. (US) 1982-12-07 US claimed
US-4345470-A All plastic disposable thermometer AKZONA INCORPORATED (US) 1982-08-24 US claimed
US-4299727-A Disposable reversible thermometer AKZONA INCORPORATED (US) 1981-11-10 US claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12383480-B2 Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof KRT18, PRKCH, PRKCE THRB 1490/4885MAPK1 369/4885TDP1 2593/4885
US-20250041181-A1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KRT18, PRKCH, PRKCE THRB 1490/4885MAPK1 369/4885TDP1 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.