SCHEMBL1105099

SCHEMBL1105099

c1ccc(-c2ccc(-c3nnc(-c4nnc(-c5ccc(-c6ccccc6)cc5)o4)o3)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 15/20 0.85
RAB9A P51151 15/20 0.85
SMN1; SMN2 Q16637 9/20 0.85
HPGD P15428 7/20 0.76
ALDH1A1 P00352 5/20 0.76
KDM4E B2RXH2 4/20 0.76
HSD17B10 Q99714 2/20 0.76
GLA P06280 1/20 0.76
MAPT P10636 1/20 0.76
ALOX15 P16050 1/20 0.76
NFKB1 P19838 2/20 0.72
NFKB2 Q00653 2/20 0.72
RELA Q04206 2/20 0.72
POLB P06746 1/20 0.72
MEN1 O00255 1/20 0.72
KMT2A Q03164 1/20 0.72
ATAD2 Q6PL18 1/20 0.68
GAA P10253 1/20 0.66
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22858502 0.97 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL522555 0.97 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL46424 0.97 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL74999 0.97 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL4343181 0.95 NPC1 (0.94) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL46426 0.92 NPC1 (1.00) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL12306750 0.89 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL12765574 0.89 RAB9A (0.76) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL12111793 0.89 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL19391492 0.89 NPC1 (0.74) NPC1RAB9ASMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8154014-B2 Organic thin film transistor and organic thin film light-emitting transistor IDEMITSU KOSAN, CO., LTD. (JP) 2012-04-10 US disclosed
US-8154014-B2 Organic thin film transistor and organic thin film light-emitting transistor IDEMITSU KOSAN, CO., LTD. (JP) 2012-04-10 US disclosed
US-20100244000-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-09-30 US disclosed
US-20100244000-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO., LTD. (JP) 2010-09-30 US disclosed