Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.90 |
| ▸ | RAB9A | P51151 | 15/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.90 |
| ▸ | HPGD | P15428 | 7/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.79 |
| ▸ | GLA | P06280 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.75 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.75 |
| ▸ | RELA | Q04206 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22858502 | 1.00 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL74999 | 1.00 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL46424 | 1.00 | NPC1 (0.90) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL1105099 | 0.97 | NPC1 (0.85) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL4343181 | 0.97 | NPC1 (0.94) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL46426 | 0.95 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12306750 | 0.91 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12765574 | 0.91 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12111793 | 0.91 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL19391492 | 0.91 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884994-B2 | High temperature scintillator | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2005-04-26 | — | — | US | claimed |
| US-20040056186-A1 | High temperature scintillator | SCHLUMBERGER TECHNOLOGY CORPORATION | 2004-03-25 | — | — | US | claimed |
| US-6538725-B2 | Method for determination of structural defects of coatings | GENERAL ELECTRIC COMPANY | 2003-03-25 | — | — | US | claimed |
| US-20020135758-A1 | Method for determination of structural defects of coatings | GENERAL ELECTRIC COMPANY | 2002-09-26 | — | — | US | claimed |
| US-20010045529-A1 | Double-resonance-absorption microscope | OLYMPUS CORPORATION (JP) | 2001-11-29 | — | — | US | claimed |
| US-20260137591-A1 | COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS | ICU MEDICAL INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12521309-B2 | Compositions and devices for containing medical fluids | ICU MEDICAL, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| US-20250336470-A1 | SYSTEM AND METHOD FOR USING GRAPH NEURAL NETWORK ARCHITECTURE FOR PREDICTING DRUG-TARGET INTERACTIONS | EDAMMO INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | UNIVERSITY OF WASHINGTON | 2025-04-03 | — | — | US | disclosed |
| CN-119005757-B | Environment variable driven perchlorate point source pollution treatment method and system | 湖南大学 | 2025-01-03 | — | — | CN | disclosed |
| EP-4479475-A2 | MULTIPHASED POLYHYDROXYALKANOATE-BASED COMPOSITIONS AND ARTICLES MADE THEREFROM | Newlight Technologies, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| US-12157271-B2 | Additive manufacturing with dye-infused feed material | GM Global Technology Operations LLC (US) | 2024-12-03 | — | — | US | disclosed |
| US-6368778-B1 | FLUORENONE, FLUORENE, COUMARIN, NAPHTHALIC ACID IMIDE, PYRAZOLINE, OR ANTHRACENE IMAGE STABILIZER COMPOUNDS IN THE SILVER LAYER REDUCE IMAGE BROWNING; STABLE TO LIGHT AND HEAT OVER TIME PARTICULARLY UNDER LIGHT-BOX CONDITIONS | EASTMAN KODAK COMPANY | 2002-04-09 | — | — | US | disclosed |
| EP-1180805-A2 | An oled fiber light source | GENERAL ELECTRIC COMPANY (US) | 2002-02-20 | — | — | EP | disclosed |
| EP-1180722-A2 | Photothermographic materials providing improved image stability and methods of use | EASTMAN KODAK COMPANY (US) | 2002-02-20 | — | — | EP | disclosed |
| US-20010045529-A1 | Double-resonance-absorption microscope | OLYMPUS CORPORATION (JP) | 2001-11-29 | — | — | US | disclosed |
| US-20010033135-A1 | Organic electroluminescent devices with enhanced light extraction | ATLANTIC PARK STRATEGIC CAPITAL FUND, L.P., AS COLLATERAL AGENT | 2001-10-25 | — | — | US | disclosed |
| EP-1121000-A2 | Light source with organic layer and photoluminsecent layer | GENERAL ELECTRIC COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-1120838-A2 | Organic light emitting device and method for mounting | GENERAL ELECTRIC COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-1111966-A2 | Luminescent display and method of making | GENERAL ELECTRIC COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260137591-A1 | COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS | TFEB, LAGE3, RICTOR | NPC1 3126/4885RAB9A 2768/4885SMN1; SMN2 1265/4885 |
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | DHFR, CCNH, ODC1 | NPC1 2613/4885RAB9A 4418/4885SMN1; SMN2 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.