SCHEMBL11054800

SCHEMBL11054800

C/C(N)=C/C(=O)OCCN1C(=O)N(CCOC(=O)/C=C(/C)N)C(C)(C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5808485 0.82 TSHR (0.42) PLA2G7
SCHEMBL11332808 0.82 ALDH1A1 (0.41) PLA2G7
SCHEMBL10878204 0.75 PLA2G7 (0.42) PLA2G7
SCHEMBL22722643 0.75 PLA2G7 (0.39) PLA2G7
SCHEMBL11054796 0.75 TAS2R8 (0.30) PLA2G7
SCHEMBL10676530 0.70 MEN1 (0.60)
SCHEMBL9673762 0.70 MEN1 (0.60)
SCHEMBL11527032 0.70 PLA2G7 (0.41) PLA2G7
SCHEMBL3295702 0.69 TSHR (0.39)
SCHEMBL11430119 0.69 PLA2G7 (0.40) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4424336-A Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound CIBA-GEIGY CORPORATION (US) 1984-01-03 US disclosed
US-4360655-A Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine CIBA-GEIGY CORPORATION (US) 1982-11-23 US disclosed
US-4348511-A POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed
US-4291146-A Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives CIBA-GEIGY CORPORATION (US) 1981-09-22 US disclosed
US-4161580-A Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4089845-A Thermosetting mixtures which are stable on storage from polyimide and .beta. CIBA-GEIGY CORPORATION (US) 1978-05-16 US disclosed